BDBM792927 US12552795, Compound 4::US20260138986, Compound 4
SMILES C[C@](N)(c1ccc(F)cc1)c1cnc(N2CCN(c3ncnn4cc(-c5cnn(CCO)c5)cc34)CC2)nc1
InChI Key InChIKey=IPMARPMXSFFZFG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 792927
Affinity DataKd: <0.300nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Affinity DataKd: <0.300nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Affinity DataKd: 17.5nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataKd: 17.5nMAssay Description:Kd Determinations. For most assays, including wt KIT kinase, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 st...More data for this Ligand-Target Pair
Affinity DataIC50: 7.13E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 7.13E+3nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair