BDBM808383 6-benzyl-3-(2- {[(3S)-piperidin- 3-yl]amino}-5- (trifluoromethyl)py- rimidin-4-yl)- 1H,6H,7H- pyrrolo[2,3- c]pyridin-7-one::US20260137698, Compound CDK7-961
SMILES O=c1c2[nH]cc(-c3nc(N[C@H]4CCCNC4)ncc3C(F)(F)F)c2ccn1Cc1ccccc1
InChI Key InChIKey=MGPCIUBMNMXHRM-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 808383
Affinity DataIC50: 5nMAssay Description:MYLK dissociation constants (Kd) for compounds were determined using the DiscoverX KdELECT platform. The MYLK kinase (accession number NP_444254.3) w...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 69nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 125nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 200nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.70E+3nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
Ligand Info