BDBM808410 6-(3,5- dimethyl-1,2- oxazol-4-yl)-3- (2-{[(3S)- piperidin-3- yl]amino}-5- (trifluoromethyl) pyrimidin-4- yl)-1H,6H,7H- pyrrolo[2,3- c]pyridin-7- one::US20260137698, Compound CDK7-924
SMILES Cc1noc(C)c1-n1ccc2c(-c3nc(N[C@H]4CCCNC4)ncc3C(F)(F)F)c[nH]c2c1=O
InChI Key InChIKey=BBAMUKCLMSHOJW-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 808410
Affinity DataIC50: 5nMAssay Description:MYLK dissociation constants (Kd) for compounds were determined using the DiscoverX KdELECT platform. The MYLK kinase (accession number NP_444254.3) w...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 200nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 200nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 431nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7.80E+3nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
Ligand Info