BDBM10000 (4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyridin-3-ylmethanol::6-Methoxybenzofuran-2-yl-(4-fluorophenyl)-3-pyridylmethanol::Benzofuran Pyridine Derivative 4a

SMILES COc1ccc2cc(oc2c1)C(O)(c1ccc(F)cc1)c1cccnc1

InChI Key InChIKey=HBDRSBZVRRBXMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10000   

TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM10000((4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione [1beta-3H] as substrate incubated for 1 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM10000((4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)
Affinity DataIC50:  44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed