BDBM103828 SPI-03::US11041859, Code SPI-03

SMILES Cc1cc(ccc1-c1ccc(cc1C)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O

InChI Key InChIKey=UVHHADIQQIICAV-HVMBLDELSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 103828   

TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  2.03E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  5.17E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  1.86E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  3.00E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  2.03E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  5.17E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 3(Homo sapiens)TBA
LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of SENP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  3.00E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  3.80E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  2.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 7(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  4.80E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of SENP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of SENP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSmall ubiquitin-related modifier 1/2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  1.86E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent