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Found 4 Enz. Inhib. hit(s) with Target = 'Sentrin-specific protease 1' and Ligand = 'BDBM103828'
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  1.86E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of SENP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  3.80E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope

LigandPNGBDBM103828(SPI-03 | US11041859, Code SPI-03)
Affinity DataIC50:  2.03E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed