BDBM107116 US8592423, 5,8-Dimethyl-2-(2-(4-phenyl-1-propyl-1H-imidazol-2-Acyclopropyl)-[1,2,4]triazolo[1,5-a]pyrazine

SMILES CCCn1cc(nc1C1CC1c1nc2c(C)ncc(C)n2n1)-c1ccccc1

InChI Key InChIKey=IJCQEHMWMZVVTK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107116   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM107116(US8592423, 5,8-Dimethyl-2-(2-(4-phenyl-1-propyl-1H...)
Affinity DataIC50:  6.65nMAssay Description:PDE10 activity was measured using Scintillation Proximity Assay (SPA)-based methods. PDE10 catalyses the hydrolysis of the intracellular messenger ad...More data for this Ligand-Target Pair
In DepthDetails US Patent