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Found 1 Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM107116'
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM107116(US8592423, 5,8-Dimethyl-2-(2-(4-phenyl-1-propyl-1H...)
Affinity DataIC50:  6.65nMAssay Description:PDE10 activity was measured using Scintillation Proximity Assay (SPA)-based methods. PDE10 catalyses the hydrolysis of the intracellular messenger ad...More data for this Ligand-Target Pair
In DepthDetails US Patent