BDBM11995 2-chloro-5-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid::Interchim compound 57
SMILES Cc1ccc(C)n1-c1ccc(Cl)c(c1)C(O)=O
InChI Key InChIKey=ZKMKAGTWPRBWAK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 11995
Affinity DataKi: 5.60E+3nM ΔG°: -7.21kcal/mole IC50: 6.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, the concentrations of inhibitor that caused 50% inhibition of enzymati...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Sciences
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Tdp1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair