BDBM122704 US8735386, I-174

SMILES Cn1nc2CCc3cnc(Nc4ccccc4)nc3-c2c1-c1sccc1Cl

InChI Key InChIKey=AMICOUOSUWKIMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122704   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122704(US8735386, I-174)
Affinity DataIC50:  0.400nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In DepthDetails US Patent