BDBM12353 3-(5-methyl-1H-imidazol-1-yl)pyridine::nicotine 3-heteroaromatic analogue 6
SMILES Cc1cncn1-c1cccnc1
InChI Key InChIKey=YTNBLXMIWILWOO-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 12353
Affinity DataKi: 500nM ΔG°: -8.94kcal/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
Affinity DataKi: 5.45E+4nMAssay Description:To measure CYP3A4 activity, testosterone 6-hydroxylation was determined. After reactions were terminated, the organic phase was collected and removed...More data for this Ligand-Target Pair