BDBM12657 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsulfonyl)-[1,1-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::1-[3-(aminomethyl)phenyl]-N-[2-fluoro-4-(2-methanesulfonylphenyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::CHEMBL559015::DPC 423::DPC423
SMILES CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2cc(nn2-c2cccc(CN)c2)C(F)(F)F)c(F)c1
InChI Key InChIKey=ZLUOAFAJSUPHOG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 12657
Affinity DataKi: 0.150nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Tested in vitro for inhibition of rabbit Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Tested in vitro for inhibition of human plasma KallikrieneMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Tested in vitro for inhibition of human activated protein CMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Tested in vitro for inhibition of human Coagulation factor IXMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >1.50E+4nMAssay Description:Tested in vitro for inhibition of human Coagulation factor VIIMore data for this Ligand-Target Pair
Affinity DataKi: >1.70E+4nMAssay Description:Tested in vitro for inhibition of human ChymotrypsinogenMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >1.90E+4nMAssay Description:Tested in vitro for inhibition of human Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: >3.50E+4nMAssay Description:Tested in vitro for inhibition of human plasminMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >4.50E+4nMAssay Description:Tested in vitro for inhibition of human Tissue type plasminogen activatorMore data for this Ligand-Target Pair