BDBM156378 US9018381, 3::US9248140, 3
SMILES CN(CCO)CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(CC1)[C@@H](O)c1ccccc1-c1ccc(Cl)cc1
InChI Key InChIKey=UNEJSHNDABUZNY-UJNHCCGESA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 156378
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
Affinity DataIC50: <0.300nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of synthetic peptide tracer conjugated to fluorescein isothiocyanate from C-terminal 6xHis-tagged Bcl-xL (1 to 209 residues) (unknown or...More data for this Ligand-Target Pair
Affinity DataIC50: <0.300nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Displacement of synthetic peptide tracer conjugated to fluorescein isothiocyanate from C-terminal 6xHis-tagged Bcl-2 (1 to 204 residues) (unknown ori...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair