BDBM158154 US10081622, Compound 11::US10370379, Entrectinib::US11059827, Compound Entrectinib::US11267806, Compound T-12::US9029356, 11::US9255087, 11::US9616059, 11
SMILES CN1CCN(CC1)c1ccc(C(=O)Nc2n[nH]c3ccc(Cc4cc(F)cc(F)c4)cc23)c(NC2CCOCC2)c1
InChI Key InChIKey=HAYYBYPASCDWEQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 158154
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human TrkA G667C mutant expressed in mouse NIH/3T3 cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human TrkA G595R mutant expressed in mouse NIH/3T3 cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human wild type TrkA kinase domain expressed in mouse NIH/3T3 cells by HTRF assayMore data for this Ligand-Target Pair