BDBM18355 (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol::CHEMBL1029::MIGLUSTAT::N-Butyl-DNJ::US20230339856, Compound NB-DNJ::US9181184, 5

SMILES CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key InChIKey=UQRORFVVSGFNRO-UTINFBMNSA-N

Data  5 KI  56 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18355   

TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

LigandBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)Copy SMILESCopy InChI

Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair

Target InfoNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
CHEMBLDrugBankMCE
MMDBPC cidPC sidPDBPatentsSimilars

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