BDBM189377 N-(4-(tert-butyl)benzyl)-8-imino-4-methyl-2-oxo-2H,8H-pyrano[2,3-f]chromene-9-carboxamide (4p)

SMILES Cc1cc(=O)oc2c1ccc1oc(=N)c(cc21)C(=O)NCc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=UMTKCFJRDJJORY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 189377   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yogi Vemana University

LigandPNGBDBM189377(N-(4-(tert-butyl)benzyl)-8-imino-4-methyl-2-oxo-2H...)
Affinity DataIC50:  77nMpH: 7.7Assay Description:In brief, reaction mixture composed of 10 µL of test sample of five different concentrations, 145 µL phosphate buffer 200 mM (pH 7.7), 80 µL of dithi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yogi Vemana University

LigandPNGBDBM189377(N-(4-(tert-butyl)benzyl)-8-imino-4-methyl-2-oxo-2H...)
Affinity DataIC50:  10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Yogi Vemana University

Curated by ChEMBL
LigandPNGBDBM189377(N-(4-(tert-butyl)benzyl)-8-imino-4-methyl-2-oxo-2H...)
Affinity DataIC50:  5.79E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed