BDBM19057 (2S)-3-({[(4-aminophenyl)methyl]carbamoyl}amino)-2-{[(2R)-1-(benzenesulfonyl)pyrrolidin-2-yl]formamido}propanoic acid::prolyl-2,3-diaminopropionic acid (DAP) scaffold, 13

SMILES Nc1ccc(CNC(=O)NC[C@H](NC(=O)C2CCCN2S(=O)(=O)c2ccccc2)C(O)=O)cc1

InChI Key InChIKey=QKMRLEQVMNWNFD-OYKVQYDMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 19057   

TargetIntegrin alpha-2/beta-1 [T112H](Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM19057((2S)-3-({[(4-aminophenyl)methyl]carbamoyl}amino)-2...)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-1/beta-1 [T112H](Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM19057((2S)-3-({[(4-aminophenyl)methyl]carbamoyl}amino)-2...)
Affinity DataAssay Description:The ligand was immobilized on 96-well flat microtiter in PBS buffer solution overnight, and the wells were blocked with 1% BSA in HBSS buffer solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM19057((2S)-3-({[(4-aminophenyl)methyl]carbamoyl}amino)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:The ligand was immobilized on 96-well flat microtiter in acetic acid solution overnight, and the wells were blocked with 1% BSA in HyQ HBSS buffer co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM19057((2S)-3-({[(4-aminophenyl)methyl]carbamoyl}amino)-2...)
Affinity DataIC50:  1.97E+3nMAssay Description:The ligand was immobilized on 96-well flat microtiter in acetic acid solution overnight, and the wells were blocked with 1% BSA in HyQ HBSS buffer co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-2/beta-1 [T112H](Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM19057((2S)-3-({[(4-aminophenyl)methyl]carbamoyl}amino)-2...)
Affinity DataIC50:  102nMAssay Description:The ligand was immobilized on 96-well flat microtiter in PBS buffer solution overnight, and the wells were blocked with 1% BSA in HBSS buffer solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed