BDBM191572 6-(3-chlorophenyl)pteridine-2,4,7-triamine (15)::Epiblastin A

SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1cccc(Cl)c1

InChI Key InChIKey=ZWNKKZSRANLVEW-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 191572   

TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  8.90E+3nMAssay Description:Single-point measurements analyses and subsequent dose-dependent investigations of selected pteridine derivatives for inhibition of CK1α were pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  500nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  4.70E+3nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  3.81E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  2.74E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  8.30E+3nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  4.51E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase BRSK1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)
Affinity DataIC50:  2.42E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed