BDBM20182 (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::25-Hydroxycholesterol (25OH)::25-hydroxycholesterol
SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@]([H])(O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)(C)O
InChI Key InChIKey=INBGSXNNRGWLJU-ZHHJOTBYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 20182
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo
Curated by ChEMBL
The University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 630nMAssay Description:Induction of human HMGCR-dCat-ELuc degradation expressed in HEK293 cells assessed as reduction in luciferase activity after 4 hrs by luciferase repor...More data for this Ligand-Target Pair