BDBM21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin
SMILES CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
InChI Key InChIKey=ZHUJMSMQIPIPTF-IBURTVSXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 21025
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Concentration required to inhibit the specific binding of tritiated ligand [3H]DADL to opiate receptor by 50%More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Compound was tested for antagonistic activity against opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Agonistic activity for Opioid receptor mu 1 as inhibitory activity towards electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 447nMAssay Description:Agonistic activity towards Opioid receptor delta 1 as inhibitory activity towards electrically stimulated mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of [3H]- DAMGO binding to Rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International
Curated by PDSP Ki Database
Sri International
Curated by PDSP Ki Database
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of [3H]- U69,593 binding to Guinea pig Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by ChEMBL
National Institute Of Environmental Health Sciences
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]- DADLE binding to Rat brain Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:The opioid activity against the mu-receptor in the isolated guinea pig ileum(GPI)More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by ChEMBL
National Institute Of Environmental Health Sciences
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
Affinity DataIC50: 447nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International
Curated by PDSP Ki Database
Sri International
Curated by PDSP Ki Database
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]-U-69,593 radioligand binding to Guinea pig Opioid receptor kappa 1; not determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in longitudinal muscle preparation of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibitory potency against delta Opioid receptor delta 1 in longitudinal muscle preparation of mouse vas deferensMore data for this Ligand-Target Pair