BDBM21340 6-aza-UMP::C6-Uridine Derivative, 18::{[(2R,3S,4R,5R)-5-(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)n1ncc(=O)[nH]c1=O
InChI Key InChIKey=LRVZOSYMNMNQFR-SHUUEZRQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 21340
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 64nMAssay Description:Inhibition of Saccharomyces cerevisiae ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.10E+3nM ΔG°: -8.45kcal/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 1.24E+4nM ΔG°: -7.36kcal/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute
Toronto General Research Institute
Affinity DataKi: 1.24E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair