Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Orotidine 5'-phosphate decarboxylase' and Ligand = 'BDBM21340'
TargetOrotidine 5'-phosphate decarboxylase(Saccharomyces cerevisiae)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  64nMAssay Description:Inhibition of Saccharomyces cerevisiae ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.24E+4nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.24E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair