BDBM21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole
SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34
InChI Key InChIKey=WIYUZYBFCWCCQJ-XEWUMVRVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 35 hits for monomerid = 21864
Affinity DataKi: 0.00720nMAssay Description:Tested for binding activity against delta1 opioid receptor using [3H]DPDPE ligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]-DPDPE (delta 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of opioid receptor muMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity against delta-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Compound was evaluated for binding affinity at Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Binding affinity against Opioid receptor delta 1 receptor binding in ICR mouse brain membranes using the radioligand [3H]naltrindoleMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]- diprenorphine from delta receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293More data for this Ligand-Target Pair
Affinity DataKi: 1.23nMAssay Description:Displacement of [3H]diprenorphine from k-Y312A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.82nMAssay Description:Displacement of [3H]- diprenorphine from delta-W284E-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity against mu-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Compound was evaluated for binding affinity at Opioid receptor mu 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Binding affinity against Opioid receptor mu 1 binding in ICR mouse brain membranes using the radioligand [3H][Ala2,Glyol5]enkephalinMore data for this Ligand-Target Pair
Affinity DataKi: 13.5nMAssay Description:Displacement of [3H]- diprenorphine from mu-K303E-receptor expressed in HEK 293More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Tested for binding activity against kappa opioid receptor using [3H]U-69593 ligandMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Tested for binding activity against mu opioid receptor using [3H]DAMGO ligandMore data for this Ligand-Target Pair
Affinity DataKi: 25.5nMAssay Description:Displacement of [3H]diprenorphine from opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 34.4nMAssay Description:Displacement of [3H]- diprenorphine from mu-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]diprenorphine from k-E297A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:Compound was evaluated for binding affinity of Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:Binding affinity against kappa-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
Affinity DataKi: 355nMAssay Description:Binding affinity against Opioid receptor kappa 1 binding in ICR mouse brain membranes using the radioligand [3H]U-69593More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Antagonist activity against mu-opioid receptor in guinea pig ileum in the presence of morphineMore data for this Ligand-Target Pair
Affinity DataIC50: 4.59E+5nMAssay Description:Antagonist activity against delta-opioid receptor in mouse vas deferens in the presence of DADLEMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity against kappa-opioid receptor in guinea pig ileum in the presence of ethylketazocineMore data for this Ligand-Target Pair