BDBM22167 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine::CHEMBL26320::CHEMBL434080::GBR 12935::GBR-12935
SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1
InChI Key InChIKey=RAQPOZGWANIDQT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 22167
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 73nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 2.09E+3nMAssay Description:Binding affinity for serotonin transporter using [125I]RTI-55More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]dopamine reuptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 165nMAssay Description:Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair