BDBM221688 US10568884, Cpd 9::US9314464, 9::US9593100, Compound 9::USRE49556, Compound 9
SMILES COC(=O)N[C@@H](C)CNc1nccc(n1)-c1cn(nc1-c1cc(Cl)cc(NS(C)(=O)=O)c1F)C(C)C
InChI Key InChIKey=CMJCXYNUCSMDBY-ZDUSSCGKSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 221688
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair