BDBM22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib::US11786535, Compound Rofecoxib
SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1
InChI Key InChIKey=RZJQGNCSTQAWON-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 30 hits for monomerid = 22369
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro inhibition against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro inhibitory concentration of compound required to inhibit Prostaglandin G/H synthase 1 enzyme was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro inhibitory activity of the compound against prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
Affinity DataIC50: >430nMAssay Description:In vitro inhibitory activity of the compound against prostaglandin G/H synthase 2 from ovineMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro inhibitory activity of the compound against prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-1More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 428nMAssay Description:In vitro inhibitory concentration of compound required to inhibit Prostaglandin G/H synthase 2 enzyme was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 428nMAssay Description:In vitro inhibition against ovine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:In vitro inhibitory activity of the compound against prostaglandin G/H synthase 2 from ovineMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of ovine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against ovine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of ovine prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of ovine prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-2More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 1More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair