BDBM22971 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid::CHEMBL509::Meclofenamate::Meclofenamic acid::US11337935, Compound Meclofenamic-acid::US20240002326, Compound Meclofenamic acid

SMILES Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl

InChI Key InChIKey=SBDNJUWAMKYJOX-UHFFFAOYSA-N

Data  6 KI  37 IC50  2 Kd  2 EC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22971   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  2.40E+4nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  2.40E+4nMAssay Description:Compound was evaluated in an intact RBL-1 cell line for inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated in an intact RBL-1 cell line for inhibition of 5-CyclooxygenaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  100nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat posterior cortex by [3H]-BRL 43694 displacement.More data for this Ligand-Target Pair