BDBM23223 7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-yl)naphthalen-2-yl]-2,3,8-trihydroxy-6-methyl-4-(propan-2-yl)naphthalene-1-carbaldehyde::CHEMBL51483::Gossypol::Gossypol (C9)::Gossypol, 4::Pogosin::Tash 1::US9115061, Gossypol::cid_3503
SMILES CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
InChI Key InChIKey=QBKSWRVVCFFDOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 23223
Affinity DataKd: 1.71E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.38E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKd: 2.32E+3nMAssay Description:Binding affinity to cMcl-1 (residues 171 to 327) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKd: 2.65E+3nMAssay Description:Binding affinity to his-tagged Mcl-1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 4.80E+3nMAssay Description:Binding affinity to Bcl2 (unknown origin) expressed in Escherichia coli BL21 by ITC assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKd: 2.65E+3nMAssay Description:Binding affinity to Mcl1 (unknown origin) expressed in Escherichia coli BL21 by ITC assayMore data for this Ligand-Target Pair