BDBM23707 1-[(2-fluorophenyl)carbonyl]-5-methyl-3-nitro-1H-pyrazole::N-Benzoylpyrazole deriv., 9
SMILES Cc1cc(nn1C(=O)c1ccccc1F)[N+]([O-])=O
InChI Key InChIKey=INYGHXGUCFFZOM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 23707
Affinity DataKi: 107nM ΔG°: -9.50kcal/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Thrombin activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration o...More data for this Ligand-Target Pair
Affinity DataAssay Description:Cathepsin D assays were monitored with a Fluoroskan Ascent FL microtiter plate reader at excitation and emission wavelengths of 340 and 390 nm, respe...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Kallikrein activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration...More data for this Ligand-Target Pair
Affinity DataAssay Description:Reactions for aminopeptidase M activity were monitored at 405 nm using a SpectraMax Plus microplate reader. For all compounds tested, the concentrati...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Chymotrypsin activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentrati...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Urokinase activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration ...More data for this Ligand-Target Pair