BDBM23765 3-{[4-(4-tetradecylpiperazin-1-yl)phenyl]methyl}-4,5-dihydro-1,2,4-oxadiazol-5-one::PMS 1062 piperazine deriv., 27a

SMILES CCCCCCCCCCCCCCN1CCN(CC1)c1ccc(Cc2nc(=O)o[nH]2)cc1

InChI Key InChIKey=ADGVIZHVXUKABB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23765   

TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23765(3-{[4-(4-tetradecylpiperazin-1-yl)phenyl]methyl}-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue as the substrate. The increase in fluorescence (ex @342 nm and em@388 nm) of the enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23765(3-{[4-(4-tetradecylpiperazin-1-yl)phenyl]methyl}-4...)
Affinity DataIC50:  4.50E+3nMpH: 7.5 T: 2°CAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed