BDBM23770 3-{[4-(tetradecyloxy)phenyl]methyl}-4,5-dihydro-1,2,4-oxadiazol-5-one::CHEMBL219947::PMS 1062

SMILES CCCCCCCCCCCCCCOc1ccc(Cc2nc(=O)o[nH]2)cc1

InChI Key InChIKey=ANLYQPBTEGWYHJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23770   

TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23770(3-{[4-(tetradecyloxy)phenyl]methyl}-4,5-dihydro-1,...)
Affinity DataIC50:  4.00E+3nMpH: 7.5 T: 2°CAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23770(3-{[4-(tetradecyloxy)phenyl]methyl}-4,5-dihydro-1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue as the substrate. The increase in fluorescence (ex @342 nm and em@388 nm) of the enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23770(3-{[4-(tetradecyloxy)phenyl]methyl}-4,5-dihydro-1,...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant group 2A phospholipase A2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23770(3-{[4-(tetradecyloxy)phenyl]methyl}-4,5-dihydro-1,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human group IIA PLA2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23770(3-{[4-(tetradecyloxy)phenyl]methyl}-4,5-dihydro-1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine group 1B phospholipase A2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23770(3-{[4-(tetradecyloxy)phenyl]methyl}-4,5-dihydro-1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig group IB PLA2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed