BDBM237921 US9394285, 2

SMILES OCc1ccc(cc1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O

InChI Key InChIKey=NOGWJYQSYBAMTO-UHFFFAOYSA-N

Data  1 Kd  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237921   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM237921(US9394285, 2)Copy SMILESCopy InChI

Affinity DataEC50:  53nMAssay Description:Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphoryl...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM237921(US9394285, 2)Copy SMILESCopy InChI

Affinity DataKd:  150nMAssay Description:Binding affinity to recombinant human AMPK alpha1/beta1/gamma1 by SPR binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI