BDBM24515 (2E,5E)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one::Thiazole analogue, 2
SMILES COc1cc(\C=C2\S\C(NC2=O)=N\c2nccs2)ccc1O
InChI Key InChIKey=XBGLQWFAIIJBCT-YRNVUSSQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 24515
Affinity DataKi: 2.56E+4nM ΔG°: -6.26kcal/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Alexander Technological Education Institute Of Thessaloniki
Curated by ChEMBL
Alexander Technological Education Institute Of Thessaloniki
Curated by ChEMBL
Affinity DataIC50: 9.95E+4nMAssay Description:Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...More data for this Ligand-Target Pair