BDBM24525 (2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one::Benzothiazolyl- analogue, 12

SMILES COc1cc(\C=C2\S\C(NC2=O)=N\c2nc3ccccc3s2)cc(OC)c1O

InChI Key InChIKey=WTYRLPROOFMPEA-OQLLNIDSSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24525   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Aristotle University

LigandPNGBDBM24525((2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(4-hydro...)
Affinity DataKi:  1.81E+4nM ΔG°:  -6.47kcal/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed