BDBM24627 1H-indazole::Indazole, 5::Indazole, 6

SMILES c1n[nH]c2ccccc12

InChI Key InChIKey=BAXOFTOLAUCFNW-UHFFFAOYSA-N

Data  5 IC50  4 Kd

PDB links: 9 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24627   

TargetDNA repair and recombination protein RadA(Pyrococcus furiosus)
University of Cambridge

LigandPNGBDBM24627(1H-indazole | Indazole, 5 | Indazole, 6)
Affinity DataKd:  1.00E+6nMAssay Description:The thermal-shift denaturation assay was performed on an iCycler iQ Real Time Detection System (BioRad) in 96-well iCycler iQ PCR plates sealed with ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM24627(1H-indazole | Indazole, 5 | Indazole, 6)
Affinity DataKd:  3.60E+5nMAssay Description:Binding affinity to recombinant ferric state of IDO1 (unknown origin) expressed in Escherichia coli assessed as dissociation constant incubated for 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM24627(1H-indazole | Indazole, 5 | Indazole, 6)
Affinity DataKd:  5.30E+3nMAssay Description:Binding affinity to human HSP90alpha assessed as 2D1H-15N chemical shift perturbation by NMR spectroscopyChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM24627(1H-indazole | Indazole, 5 | Indazole, 6)
Affinity DataKd:  8.10E+4nMAssay Description:Binding affinity to recombinant ferrous state of IDO1 (unknown origin) expressed in Escherichia coli assessed as dissociation constant incubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed