BDBM246591 Bi-lawsone analog, 3a

SMILES OC1=C(C(C2=C(O)C(=O)c3ccccc3C2=O)c2ccccc2)C(=O)c2ccccc2C1=O

InChI Key InChIKey=XWWLEUCIKOWDIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246591   

TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246591(Bi-lawsone analog, 3a)
Affinity DataIC50:  1.60E+4nMpH: 7.5Assay Description:In the preincubation assay, CPT concentrations were 50 and 100 μM, whereas various concentrations of compounds were 25, 50 and 100 μM. LdTOP1LS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246591(Bi-lawsone analog, 3a)
Affinity DataIC50:  5.10E+4nMpH: 7.5Assay Description:In simultaneous relaxation assay, CPT concentrations were 50 and 100 μM, whereas concentration of compounds were 50, 100 and 200 μM. Relaxation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed