BDBM25096 4-(2,4-diaminopteridin-6-yl)phenol::diaminopteridine derivative, 19

SMILES Nc1nc(N)c2nc(cnc2n1)-c1ccc(O)cc1

InChI Key InChIKey=FUTZONJYAAOCTH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25096   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Targegen

LigandBDBM25096(4-(2,4-diaminopteridin-6-yl)phenol | diaminopterid...)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+3nMpH: 7.4 T: 2°CAssay Description:The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI