BDBM25471 N-[4-(pyridin-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide::pyridine-phenyl, 2
SMILES O=C(Nc1ccc(cc1)-c1ccncc1)C1COc2ccccc2O1
InChI Key InChIKey=WFRVZENQQASYRN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 25471
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 46nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
Affinity DataIC50: 6.44E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 7.05E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 692nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair