BDBM25473 N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide::pyrazole-phenyl, 4
SMILES COc1cc(ccc1NC(=O)C1COc2ccccc2O1)-c1cn[nH]c1
InChI Key InChIKey=VGRBFVDNFGSMNW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 25473
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 3.30nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
Affinity DataIC50: 8.82E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 367nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 940nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair