BDBM258468 US9522888, 693
SMILES COc1cccc(CC[C@@H]2CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)c1
InChI Key InChIKey=OPWNVYPWPMIBGP-HFRGRHLUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 258468
Affinity DataIC50: 5.20nMpH: 7.5 T: 2°CAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x10^9 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-...More data for this Ligand-Target Pair
Affinity DataEC50: >4.16E+3nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Affinity DataEC50: 19.2nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair