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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM258468'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM258468(US9522888, 693)
Affinity DataIC50:  5.20nMpH: 7.5 T: 2°CAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x10^9 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM258468(US9522888, 693)
Affinity DataEC50:  19.2nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent