BDBM26523 6-ethyl-5-(3-phenylprop-1-yn-1-yl)pyrimidine-2,4-diamine::Propargyl inhibitor, 24

SMILES CCc1nc(N)nc(N)c1C#CCc1ccccc1

InChI Key InChIKey=LZRXPKDKRFTIGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26523   

TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM26523(6-ethyl-5-(3-phenylprop-1-yn-1-yl)pyrimidine-2,4-d...)
Affinity DataIC50:  360nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

LigandPNGBDBM26523(6-ethyl-5-(3-phenylprop-1-yn-1-yl)pyrimidine-2,4-d...)
Affinity DataIC50:  3.20E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed