BDBM27210 (2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]butanamide::Conessine analogue, 13c
SMILES [H][C@@]1(C)N(C)C[C@]23CC[C@@]4([H])[C@@]([H])(CC=C5C[C@H](CC[C@]45C)N(C)C(=O)[C@H](NC)C(C)C)[C@]2([H])CC[C@]13[H]
InChI Key InChIKey=DFTFGLPAHCOAEP-TVSVWYSMSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 27210
Affinity DataKi: 0.210nM ΔG°: -13.2kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.57nMAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 2.57nMAssay Description:Displacement of [3H]N-alpha methyl histamine from rat cortical membrane histamine H3 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair