Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM27210'
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27210((2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,...)
Affinity DataKi:  0.210nM ΔG°:  -55.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27210((2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27210((2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,...)
Affinity DataKi:  2.57nMAssay Description:Displacement of [3H]N-alpha methyl histamine from rat cortical membrane histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27210((2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,...)
Affinity DataKi:  2.57nMAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed