BDBM276174 2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 81::US10233173, Example 81

SMILES Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(F)(F)F)nc1

InChI Key InChIKey=HCENSGGANKMNMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276174   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276174(2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-...)
Affinity DataIC50:  3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276174(2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent