BDBM285022 2-methyl-4-(1,3-oxazol-2-yl)isoquinolin- 1-one::US10023592, Example 67::US10941160, Example 67

SMILES Cn1cc(-c2ncco2)c2ccccc2c1=O

InChI Key InChIKey=VYVPGIUGYNRIJA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285022   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285022(2-methyl-4-(1,3-oxazol-2-yl)isoquinolin- 1-one | U...)
Affinity DataIC50: >5.00E+3nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent