BDBM293441 US10106527, Compound 27::US10544128, Compound 27::US11548872, Compound 27::US20230286945, Compound 27::US9951048, Compound 27

SMILES CNC(=O)c1ccc(cn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(c1)C1CCN(C)CC1

InChI Key InChIKey=PEEFLVWYURCVRE-UHFFFAOYSA-N

Data  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293441   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM293441(US10106527, Compound 27 | US10544128, Compound 27 ...)
Affinity DataEC50: >1.00E+4nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM293441(US10106527, Compound 27 | US10544128, Compound 27 ...)
Affinity DataEC50:  33.3nMAssay Description:The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies-a Divis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent