BDBM303716 (3S)-N-[5-[2-(4- chlorophenyyl) ethyl]isoxazol- 3-yl]-5-oxo-1-[4-(1- piperidylmethyl)phenyl] pyrrolidine-3- carboxamide::US10138230, Example F146

SMILES [H][C@]1(CN(C(=O)C1)c1ccc(CN2CCCCC2)cc1)C(=O)Nc1cc(CCc2ccc(Cl)cc2)on1

InChI Key InChIKey=HEZRTVZAKSUXEF-QFIPXVFZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303716   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM303716((3S)-N-[5-[2-(4- chlorophenyyl) ethyl]isoxazol- 3-...)
Affinity DataIC50:  1nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent