BDBM32705 2-methyl-N-(3-methyl-1,3-thiazol-2-ylidene)benzamide::2-methyl-N-(3-methyl-2-thiazolylidene)benzamide::2-methyl-N-(3-methyl-4-thiazolin-2-ylidene)benzamide::2-methyl-N-[3-methyl-1,3-thiazol-2(3H)-yliden]benzenecarboxamide::MLS000541577::SMR000126435::cid_3710007

SMILES Cc1ccccc1C(=O)N=c1sccn1C

InChI Key InChIKey=WBNLCFOVCGUFTD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 32705   

TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32705(2-methyl-N-(3-methyl-1,3-thiazol-2-ylidene)benzami...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:HTS was performed on a total of 33,068 compounds of the MLSCN library, 23,017 of which were not in the mixture HTS plates used previously. These comp...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32705(2-methyl-N-(3-methyl-1,3-thiazol-2-ylidene)benzami...)
Affinity DataIC50:  5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32705(2-methyl-N-(3-methyl-1,3-thiazol-2-ylidene)benzami...)
Affinity DataIC50: >5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32705(2-methyl-N-(3-methyl-1,3-thiazol-2-ylidene)benzami...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay