Reaction Details Report a problem with these data
Target
Neutrophil cytosol factor 1 [S99G]
Ligand
BDBM32705
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)
IC50
50000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay (2008)[AID] 
Target
Name:
Neutrophil cytosol factor 1 [S99G]
Synonyms:
NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44664.39
Organism:
Homo sapiens (Human)
Description:
gi_115298672
Residue:
390
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
  
Inhibitor
Name:
BDBM32705
Synonyms:
2-methyl-N-(3-methyl-1,3-thiazol-2-ylidene)benzamide | 2-methyl-N-(3-methyl-2-thiazolylidene)benzamide | 2-methyl-N-(3-methyl-4-thiazolin-2-ylidene)benzamide | 2-methyl-N-[3-methyl-1,3-thiazol-2(3H)-yliden]benzenecarboxamide | MLS000541577 | SMR000126435 | cid_3710007
Type:
Small organic molecule
Emp. Form.:
C12H12N2OS
Mol. Mass.:
232.301
SMILES:
Cc1ccccc1C(=O)N=c1sccn1C |w:9.9|
Structure:
Search PDB for entries with ligand similarity: